Name: QU Jing

Tel/Fax: +86-10-82619655

Email: qujing@ioz.ac.cn

Education and Research Experience

Undergraduate and Graduate Education

1998-2002 School of Life Sciences, Lanzhou University, Lanzhou, China, B.S., Biochemistry

2002-2007 Institute of Biophysics, CAS Ph.D., Cell Biology

Supervisor: Chang Chen

Postdoctoral Training

2007-2010 Del E.web Neuroscience, aging and stem cell research center, Sanford/Burnham Medical Research Institute, CA, U.S.A.

Postdoctoral Fellow Supervisor: Stuart Lipton

2010-2012 Gene expression lab, The Salk Institute for Biological Research, CA, U.S.A.

Research Associate Supervisor: Juan Carlos Izpisúa Belmonte

Selected Publications

1. Wang S, Liu Z, Ye Y, Li B, Liu T, Zhang W, Liu GH, Zhang Y, Qu J^*, Xu D^*, Chen Z^*. (2018). Ectopic hTERT expression facilitates reprograming of fibroblasts derived from patients with Werner syndrome as a WS cellular model. Cell death and disease. 9(9):923. (in press)

2. Zhang W, Wan H, Feng G, Qu J1, Wang J, Jing Y, Ren R, Liu Z, Zhang L, Chen Z, Wang S, Zhao Y, Wang Z, Yuan Y, Zhou Q, Li W, Liu GH, Hu B. (2018). SIRT6 deficiency results in developmental retardation in cynomolgus monkeys. Nature. 560(7720):661-665. (1equal contribution)

3. Zhang W, Song M, Qu J^*, Liu GH^*. (2018). Epigenetic Modifications in Cardiovascular Aging and Diseases. Circ Res. 123(7):773-786. (in press)

4. Geng L, Liu Z, Zhang W^*, Li W, Wu Z, Wang W, Ren R, Su Y, Wang P, Ju Z, Chan P, Song M^*, Qu J^*, Liu GH^*. (2018). Chemical Screen Identifies a Geroprotective Role of Quercetin in Premature Aging. Protein Cell. 6:417-435. (^*Corresponding author)

5. Wu Z, Zhang W, Song M, Wang W, Wei G, Li W, Lei J, Huang Y, Sang Y, Chan P, Chen C, Qu J^*, Suzuki K^*, Belmonte JC^*, Liu GH^*. (2018). Differential stem cell aging kinetics in Hutchinson–Gilford progeria syndrome and Werner syndrome. Protein Cell. 9(4):333-350. (^*Corresponding author)

6. Wang S, Hu B, Ding Z, Dang Y, Wu J, Li D, Liu X, Xiao B, Zhang W, Ren R, Lei J, Hu H, Chen C, Chan P, Li D, Qu J^*,Tang F^*, Liu GH^*.(2018). ATF6 safeguards organelle homeostasis and cellular aging in human mesenchymal stem cells. Cell Discovery. 4(2). (^*Corresponding author)

7. Wang P, Liu Z, Zhang X, Li J, Sun L, Ju Z, Li J, Chan P, Liu GH^*, Zhang W^*, Song M^*, Qu J^*. (2018). CRISPR/Cas9-mediated Gene Knockout Reveals a Guardian Role of NF-κB/RelA in Maintaining the Homeostasis of Human Vascular Cells. Protein Cell. 2018. 11:945-965. (^*Corresponding author)

8. Yang J, Li J, Suzuki K, Liu X, Wu J, Zhang W, Ren R, Zhang W, Chan P, Izpisua Belmonte JC, Qu J^*, Tang F^*, Liu GH^*. (2017). Genetic enhancement in cultured human adult stem cells conferred by a single nucleotide recoding. Cell Res. 67(9):1178-1181. (^*Corresponding author)

9. Wang L, Yi F, Fu L, Yang J, Wang S, Wang Z, Suzuki K, Sun L, Xu X, Yu Y, Qiao J, Belmonte JC, Yang Z, Yuan Y^*, Qu J^*, Liu GH^*.(2017). CRISPR/Cas9-mediated targeted gene correction in amyotrophic lateral sclerosis patient iPSCs. Protein Cell. 8(5):365-378. (^*Corresponding author)

10. Ren R, Deng L, Xue Y, Suzuki K, Zhang W, Yu Y, Wu J, Sun L, Gong X, Luan H, Yang F, Ju Z, Ren X, Wang S, Tang H, Geng L, Zhang W, Li J, Qiao J, Xu T^*, Qu J^*, Liu GH^*. (2017). Visualization of aging-associated chromatin alterations with an engineered TALE system. Cell Res. 27:483-504. (^*Corresponding author)