Name: WANG Yan-Ling

Tel: +86-10-64807195

Email: wangyl@ioz.ac.cn

Education

1993.09-1998.06 Ph.D. in physiology, Institute of Zoology (IOZ), Chinese Academy of Sciences (CAS), Beijing (supervisor: Prof. Lin-zhi Zhuang)

1988.09-1993.07 Bachelor degree, Department of Biology, University of Science and Technology of China, Hefei

Working Experience

2004.06-present Professor, IOZ, CAS, Beijing, China

2000.10-2004.05 Associate Professor, IOZ, CAS, Beijing, China

1998.07-2000.09 Assistant Professor, IOZ, CAS, Beijing, China

1999.05-1999.09 Visiting Scholar, HongKong University, HongKong

Selected Publications

1. Shao X, Tan C, Chen D, Wang YL^*. (2018). Placental defects are involved in most gene mutations that cause embryonic and fetal death. Biol Reprod. 99(3):476-478.

2. Liu M^#, Wang Y^#, Lu H^#, Wang H, Shi X, Shao X, Li Y, Zhao Y^* and Wang YL^*. (2018). mir-518b enhances human trophoblast cell rroliferation through targeting rap1b and activating ras-MAPK signal. Frontiers in Endocrinology. 9(100).

3. Wang H^#, Zhang L^#, Guo X, Bai Y, Li YX, Sha J, Peng C, Liu M and Wang YL^*. (2018). MiR-195 modulates oxidative stress-induced apoptosis and mitochondrial energy production in human trophoblasts via FOXRED1 and PDPR. J Hypertens. 36(2):306-318.

4. Ma L^#, Li G^#, Cao G^#, Zhu Y, Du MR, Zhao Y, Wang H, Liu Y, Yang Y, Li YX, Li DJ, Yang H, Wang YL^*. (2017). dNK cells facilitate the interaction between trophoblastic and endothelial cells via VEGF-C and HGF. Immunol Cell Biol. 95(8):695-704.

5. Shao X^#, Liu Y^#, Liu M, Wang Y, Yan L, Wang H, Ma L, Lia YX, Zhao Y^*, Wang YL^*. (2017). Testosterone represses estrogen signaling via upregulating mir-22: mechanism for imbalanced steroid hormone production in preeclampsia. Hypertension. 69:721-730. (Editorial highlight)

6. Wu H^#, Wang H^#, Liu M, Bai Y, Li YX, Ji L, Peng C, Yu Y^*, Wang YL^*. (2016). MiR-195 participates in the placental disorder of preeclampsia via targeting activin receptor type-2B in trophoblastic cells. J Hypertens. 34(7):1371-9.

7. Luo R^#, Wang Y^#, Xu P^#, Cao G, Zhao Y, Shao X, Li YX, Chang C, Peng C, Wang YL^*. (2016). Hypoxia-inducible miR-210 contributes to preeclampsia via targeting thrombospondin type I domain containing 7A. Sci Rep. 6:19588.

8. Li S^#, Wang Y^#, Cao B, Wu Y, Ji L, Li YX, Liu M, Zhao Y, Qiao J, Wang H, Wang H, Han C, Wang YL^*. (2014). Maturation of GDF15 in human placental trophoblast cells depends on the interaction with matrix metalloproteinase-26 (MMP-26). J Clin Endo Metab. 99(11):E2777-87.

9. Luo R^#, Shao X^#, Xu P, Liu Y, Wang Y, Zhao Y, Liu M, Ji L, Li YX, Chang C, Qiao J, Peng C^*, Wang YL^*. (2014). MicroRNA-210 contributes to preeclampsia by down-regulating KCMF1. Hypertension. 64:839-847.

10. Xu P^#, Zhao Y^#, Liu M, Wang Y, Wang H, Li YX, Zhu X, Yao Y, Wang H, Qiao J, Ji L^*, Wang YL^*. (2014). Variations of microRNAs in human placentas and plasma from preeclamptic pregnancy. Hypertension. 63:1276-1284.