Name: LI Wei

Tel: +86-10-64807297

Email: liwei@ioz.ac.cn

Education

2006-2012 Ph.D. in Developmental Biology, at State Key Laboratory of Reproductive Biology, Institute of Zoology, CAS

2002-2006 B.Sc. in Life Sciences, at the College of Life Sciences, Wuhan University

Working Experience

2013-2015 Professor of Star Program, Principle Investigator, Group leader of Stem Cell and Cell Cycle Regulation, Institute of Zoology, CAS

2016-present Professor, Principle Investigator, Group leader of Stem Cell and Cell Cycle Regulation, Institute of Zoology, CAS

2017.09-Present Vice Director of State Key Laboratory of Stem Cell and Reproductive Biology

Selected Publications

1. Zhang W^#, Wan H^#, Feng G^#, Qu J#, Wang J, Jing Y, Ren R, Liu Z, Zhang L, Chen Z, Wang S, Zhao Y, Wang Z, Yuan Y, Zhou Q, Li W^*, Liu G^*, Hu B^*. (2018). SIRT6 deficiency results in developmental retardation in cynomolgus monkeys. Nature. 560(7720):661-665.

2. Wang X^#, Li T^#, Cui T^#, Yu D^#, Liu C^#, Jiang L, Feng G, Wang L, Fu R, Zhang X, Hao J, Wang Y, Wang L, Zhou Q^*, Li W^*, Hu B^*. (2018). Human embryonic stem cells contribute to embryonic and extraembryonic lineages in mouse embryos upon inhibition of apoptosis. Cell Research. 28(1):126-129.

3. Wu J^#, Xu J^#, Liu B^#, Yao G^#, Wang P^#, Lin Z^#, Huang B, Wang X, Li T, Shi S, Zhang N, Duan F, Ming J, Zhang X, Niu W, Song W, Jin H, Guo Y, Dai S, Hu L, Fang L, Wang Q, Li Y, Li W, Na J^*, Xie W^*, Sun Y^*. (2018). Chromatin analysis in human early development reveals epigenetic transition during ZGA. Nature. 557(7704):256-260. (Epub ahead of print)

4. Wang CX^#, Cui GS^#, Liu X^#, Xu K^#, Wang M^#, Zhang XX, Jiang LY, Li A, Yang Y, Lai WY, Sun BF, Jiang GB, Wang HL, Tong WM, Li W, Wang XJ^*, Yang YG^*, Zhou Q^*. (2018). METTL3-mediated m6A modification is required for cerebellar development. PLoS Biol. 16(6).

5. Wang YK^#, Zhu WW^#, Wu MH^#, Wu YH, Liu ZX, Liang LM, Sheng C, Hao J, Wang L, Li W, Zhou Q^*, Hu BY^*. (2018). Human Clinical-Grade Parthenogenetic ESC-Derived Dopaminergic Neurons Recover Locomotive Defects of Nonhuman Primate Models of Parkinson's Disease. Stem Cell Reports. 11(1):171-182. (Epub ahead of print)

6. Zhang W, Feng G, Wang L, Teng F, Wang L, Li W, Zhang Y^*, Zhou Q^*. (2018). MeCP2 deficiency promotes cell reprogramming by stimulating IGF1/AKT/mTOR signaling and activating ribosomal protein-mediated cell cycle gene translation. J Mol Cell Biol. 10(6):515-526. (Epub ahead of print)

7. Zhang Y^#, Guo L^#, Li Y^#, Feng GH, Teng F, Li W, Zhou Q^*. (2018). MicroRNA-494 promotes cancer progression and targets adenomatous polyposis coli in colorectal cancer. Mol Cancer. 17(1):1.

8. Zhang Y^#, Cui P^#, Li Y^#, Feng G, Tong M, Guo L, Li T, Liu L, Li W, Zhou Q^*. (2018). Mitochondrially produced ATP affects stem cell pluripotency via Actl6a-mediated histone acetylation. FASEB J. 32(4):1891-1902. (Epub ahead of print)

9. Tan Y^#, Han P^#, Gu Q^#, Chen G, Wang L, Ma R, Wu J, Feng C, Zhang Y, Wang L, Hu B, Li W, Hao J, Zhou Q^*. (2018). Generation of Clinical-grade Functional Cardiomyocytes from Human Embryonic Stem Cells in Chemically Defined Conditions. J Tissue Eng Regen Med. 12(1):153-163.

10. Li T^#, Wang L^#, Zhang X^#, Jiang L^#, Li Y, Mao J, Cui T, Li W, Wang L^*, Zhou Q^*. (2018). Generation of rat-mouse chimeras by introducing single cells of rat inner cell masses into mouse blastocysts. J Genet Genomics. 45(6):325-328. (Epub ahead of print)