LI Wei 李伟
Name: LI Wei
Tel: 64807297
Email: liwei@ioz.ac.cn
Education:
2006-2012: Ph.D. in Developmental Biology, at State Key Laboratory of Reproductive Biology, Institute of Zoology, CAS
2002-2006: B.Sc. in Life Sciences, at the College of Life Sciences, Wuhan University
Working Experience:
2013-2015: Professor of Star Program, Principle Investigator, Group leader of Stem Cell and Cell Cycle Regulation, Institute of Zoology, CAS
2016-Ongoing: Professor, Principle Investigator, Group leader of Stem Cell and Cell Cycle Regulation, Institute of Zoology, CAS
2017.09-Ongoing: Vice Director of State Key Laboratory of Stem Cell and Reproductive Biology
Selected Publications:
1. Zhang W#, Wan H#, Feng G#, Qu J#, Wang J, Jing Y, Ren R, Liu Z, Zhang L, Chen Z, Wang S, Zhao Y, Wang Z, Yuan Y, Zhou Q, Li W*, Liu G*, Hu B*. SIRT6 deficiency results in developmental retardation in cynomolgus monkeys. Nature. In press.
2. Wang X#, Li T#, Cui T#, Yu D#, Liu C#, Jiang L, Feng G, Wang L, Fu R, Zhang X, Hao J, Wang Y, Wang L, Zhou Q*, Li W*, Hu B*. (2018) Human embryonic stem cells contribute to embryonic and extraembryonic lineages in mouse embryos upon inhibition of apoptosis. Cell Res. 28(1):126-129.
3. Wu J#, Xu J#, Liu B#, Yao G#, Wang P#, Lin Z#, Huang B, Wang X, Li T, Shi S, Zhang N, Duan F, Ming J, Zhang X, Niu W, Song W, Jin H, Guo Y, Dai S, Hu L, Fang L, Wang Q, Li Y, Li W, Na J*, Xie W*, Sun Y*. (2018) Chromatin analysis in human early development reveals epigenetic transition during ZGA. Nature 557(7704):256-260. doi: 10.1038/s41586-018-0080-8. Epub 2018 May 2. 2018 Jun 20. doi: 10.1038/s41586-018-0267-z. [Epub ahead of print]
4. Wang CX#, Cui GS#, Liu X#, Xu K#, Wang M#, Zhang XX, Jiang LY, Li A, Yang Y, Lai WY, Sun BF, Jiang GB, Wang HL, Tong WM, Li W, Wang XJ*, Yang YG*, Zhou Q*. (2018) METTL3-mediated m6A modification is required for cerebellar development. PLoS Biol. 2018 Jun 7;16(6):e2004880. doi: 10.1371/journal.pbio.2004880. eCollection 2018 Jun.
5. Wang YK#, Zhu WW#, Wu MH#, Wu YH, Liu ZX, Liang LM, Sheng C, Hao J, Wang L, Li W, Zhou Q*, Hu BY*. (2018) Human Clinical-Grade Parthenogenetic ESC-Derived Dopaminergic Neurons Recover Locomotive Defects of Nonhuman Primate Models of Parkinson's Disease. Stem Cell Reports 2018 Jun 7. pii: S2213-6711(18)30227-3. doi: 10.1016/j.stemcr.2018.05.010. [Epub ahead of print]
6. Zhang W, Feng G, Wang L, Teng F, Wang L, Li W, Zhang Y*, Zhou Q*. (2018) MeCP2 deficiency promotes cell reprogramming by stimulating IGF1/AKT/mTOR signaling and activating ribosomal protein-mediated cell cycle gene translation. J Mol Cell Biol. 2018 Mar 19. doi: 10.1093/jmcb/mjy018. [Epub ahead of print]
7. Zhang Y#, Guo L#, Li Y#, Feng GH, Teng F, Li W, Zhou Q*. (2018) MicroRNA-494 promotes cancer progression and targets adenomatous polyposis coli in colorectal cancer. Mol Cancer. 2018 Jan 5;17(1):1. doi: 10.1186/s12943-017-0753-1.
8. Zhang Y#, Cui P#, Li Y#, Feng G, Tong M, Guo L, Li T, Liu L, Li W, Zhou Q*. (2018) Mitochondrially produced ATP affects stem cell pluripotency via Actl6a-mediated histone acetylation. FASEB J. 2018 Jan 5:fj201700626RR. doi: 10.1096/fj.201700626RR. [Epub ahead of print]
9. Tan Y#, Han P#, Gu Q#, Chen G, Wang L, Ma R, Wu J, Feng C, Zhang Y, Wang L, Hu B, Li W, Hao J, Zhou Q*. (2018) Generation of Clinical-grade Functional Cardiomyocytes from Human Embryonic Stem Cells in Chemically Defined Conditions. J Tissue Eng Regen Med. Jan;12(1):153-163. doi: 10.1002/term.2381. Epub 2017 Jun 9.
10. Li T#, Wang L#, Zhang X#, Jiang L#, Li Y, Mao J, Cui T, Li W, Wang L*, Zhou Q*. (2018) Generation of rat-mouse chimeras by introducing single cells of rat inner cell masses into mouse blastocysts. J Genet Genomics. 2018 May 18. pii: S1673-8527(18)30082-1. doi: 10.1016/j.jgg.2018.03.006. [Epub ahead of print]