JIN Wanzhu
Education
1999-2003 Ph.D. United Graduate School of Veterinary Sciences, Gifu University
1998-1999 N/A Tokyo University of Agriculture and Technology
1990-1994 BSc. Department of Veterinary Medicine,Yanbian University
Major Activities
2011-Current Professor Institute of Zoology, Chinese Academy of Science
2006-2010 Postdoc Joslin Diabetes Center & Harvard Medical School
2003-2006 Postdoc Riken Institute
1994-1996 Instructor YanBian University
Selected Publications
(1) Zheng Q#, Lin J#, Huang J#, Zhang H, Zhang R, Zhang X, Cao C, Hambly C, Qin G, Yao J, Song R, Jia Q, Wang X, Li Y, Zhang N, Piao Z, Ye R, Speakman JR, Wang H, Zhou Q, Wang Y*, Jin W*, Zhao J*. Reconstitution of UCP1 Using CRISPR/Cas9 in the White Adipose Tissue of Pigs Decreases Fat Deposition and Improves Thermogenic Capacity. PNAS.2017,114(45): E9474-E9482.
(2) Chuanhai Zhang#, Jingjing Wang#, Hanlin Zhang#, Shunai Liu, Hyuek Jong Lee, Wanzhu Jin*, Jun Cheng*.Hepatitis C virus core protein induces hepatic steatosis via Sirt1‐dependent pathway. Liver International.2017. DOI: 10.1111/liv.13581.
(3) Hu T#, Yuan X, Wei G, Luo H*,Lee HJ*, Jin W*.Myricetin-induced brown adipose tissue activation prevents obesity and insulin resistance in db/db mice. Eur J Nutr. 2018.57(1):391-403.
(4) Yilin You#, Xiaoxue Yuan#, Xiaomeng Liu#, Chen Liang, Minghui Meng, Yuanyuan Huang, Xue Han, Jielong Guo, Yu Guo, Chenglong Ren, Qianwen Zhang, Xiangyu Sun,Tingting Ma, Guojie Liu, Wanzhu Jin*,Weidong Huang*and Jicheng Zhan*.Cyanidin-3-glucoside increases whole body energy metabolism by upregulating brown adipose tissue mitochondrial function .Mol Nutr& Food Res.2017.61(11): 1-13.
(5) Hu T#, Yuan X#, Ye R #, Zhou H, Jun Lin, Zhang C, Hanlin Zhang, Wei G, Meng Dong, Huang Y, Lim W, Liu Q, Lee H, Jin W*. Brown adipose tissue activation by rutin ameliorates polycystic ovary syndrome in rat. JNB.2017.47:21-28.
(6) Rong Wu#, Xiao-meng Liu, Jian-guang Sun, Hong Chen, Jun Ma, Meng Dong, Shengyi Peng, Ji-qiu Wang, Jian-qing Ding, Dong-hao Li , John R Speakman, Guang Ning, Wanzhu Jin*, Zengqiang Yuan*. DJ-1 maintains energy and glucose homeostasis by regulating the function of brown adipose tissue. Cell Discovery (2017) 3, 16054:1-18.
(7) Lin J#, Cao C#, Tao C#, Ye R, Dong M, Zheng Q, Wang C, Jiang X, Qin G, Yan C,Li K,Speakman J,Wang Y*,Jin W*,Zhao J*. Cold adaptation in pigs depends on UCP 3 in beige adipocytes. JMCB. 2017. 9(5):364-375.
(8) Yuan X#, Wei G#, You Y#, Huang Y, Lee H, Dong M, Lin J, Hu T, Zhang H, Zhang C, Zhou H, Ye R, Qi X, Zhai B, Huang W, Liu S, Xie W, Liu Q, Liu X, Cui C, Li D, Zhan J, Cheng J, Yuan Z, Jin W*. Rutin ameliorates obesity through brown fat activation. the Faseb journal .2017. 31(1):333-345.
(9) Wu R#, Sun JG, Wang JQ, Li B, Liu Q, Ning G, Jin W*, Yuan Z*. c-Abl inhibition mitigates diet-induced obesity through improving insulin sensitivity of subcutaneous fat in mice. Diabetologia. 2017. 60(5):900-910.
(10) Zhang C#, Weng Y, Shi F, Jin W*.The Engrailed-1 Gene Stimulates Brown Adipogenesis .Stem Cells Int. 2016:7369491.