动物所辉凌生殖健康研究所

SUN Qing-Yuan

Date：2019-03-04 【close】

Name:	SUN Qing-Yuan
Subject:	Developmental Biology
Tel/Fax:	+86-10-64807050 /
E-mail:	sunqy@ioz.ac.cn
Address:	The State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences,1 Beichen West Road, Chaoyang District, Beijing 100101, P.R.China

Education and Training:
Ph.D. in embryology, Northeast Agricultural University (1991-1994);
Post-doc, Institute of Zoology, Chinese Academy of Sciences (1994-1996);
Post-doc, Bar-Ilan University, Israel (1996-1998);
Research associate, University of Missouri-Columbia, USA (1999-2001);
STA fellow, National Institute of Animal Industry, Japan (1996);
Invited JSPS fellow, National Institute of Agrobiological Sciences, Japan (2003); Visiting professor, University of Missouri-Columbia, USA (2005);
Invited JSPS fellow, National Institute of Agrobiological Sciences, Japan (2008);
Visiting professor, University of Missouri-Columbia, USA (2009).

Current Positions:
Professor (since 1998) State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences;
President, China Society for Reproductive Biology;
Deputy president, Chinese Society for Zoology

Vice president, Chinese Society of Medical Developmental Biology

Selected Publications:

1. Huang L, Meng TG, Ma XS, Wang ZB, Qi ST, Chen Q, Zhang QH, Liang QX, Wang ZW, Hu MW, Guo L, Ouyang YC, Hou Y, Zhao Y, Sun QY*. Rad9a is involved in chromatin decondensation and post-zygotic embryo development in mice. Cell Death Differ. 2018 Aug 28. doi: 10.1038/s41418-018-0181-9.

2. Li QN, Li L, Hou G, Wang ZB, Hou Y, Liu ZH, Schatten H, Sun QY*. Glucocorticoid exposure affects female fertility by exerting its effect on the uterus but not on the oocyte: lessons from a hypercortisolism mouse model. Hum Reprod. 2018 Dec 1;33(12):2285-2294.

3. Meng TG, Lu X, Guo L, Hou GM, Ma XS, Li QN, Huang L, Fan LH, Zhao ZH, Ou XH, OuYang YC, Schatten H, Li L, Wang ZB*, Sun QY*. Mettl14 is required for mouse postimplantation development by facilitating epiblast maturation. FASEB J. 2018 Aug 15:fj201800719R. doi: 10.1096/fj.201800719R.

4. Li J, Tang JX, Cheng JM, Hu B, Wang YQ, Aalia B, Li XY, Jin C, Wang XX, Deng SL, Zhang Y, Chen SR, Qian WP, Sun QY, Huang XX, Liu YX. Cyclin B2 can compensate for Cyclin B1 in oocyte meiosis I. J Cell Biol. 2018 Aug 10. pii: jcb.201802077. doi: 10.1083/jcb.201802077.

5. Xie B, Zhang L, Zhao H, Bai Q, Fan Y, Zhu X, Yu Y, Li R, Liang X, Sun QY, Li M, Qiao J. Poly(ADP-ribose) mediates asymmetric division of mouse oocyte. Cell Res. 2018, 28: 462-467.

6. Zhu F, Liu C, Wang F, Yang X, Zhang J, Wu H, Zhang Z, He X, Zhang Z, Zhou P, Wei Z, Shang Y, Wang L, Zhang R, Ouyang YC, Sun QY, Cao Y, Li W. Mutations in PMFBP1 Cause Acephalic Spermatozoa Syndrome. Am J Hum Genet. 2018 Aug 2;103(2):188-199.

7. Zhang T, Zhou Y, Li L, Wang ZB, Shen W, Schatten H, Sun QY*. CenpH regulates meiotic G2/M transition by modulating the APC/CCdh1-cyclin B1 pathway in oocytes. Development. 2017 Jan 15;144(2):305-312.

8. Shang Y, Zhu F, Wang L, Ouyang YC, Dong MZ, Liu C, Zhao H, Cui X, Ma D, Zhang Z, Yang X, Guo Y, Liu F, Yuan L, Gao F*, Guo X*, Sun QY*, Cao Y*, Li W*. Essential role for SUN5 in anchoring sperm head to the tail. Elife. 2017 Sep 25;6. pii: e28199. doi: 10.7554/eLife.28199.

9. Hu MW, Meng TG, Jiang ZZ, Dong MZ, Schatten H, Xu X*, Wang ZB*, Sun QY*. Protein Phosphatase 6 Protects Prophase I-Arrested Oocytes by Safeguarding Genomic Integrity. PLoS Genet. 2016 Dec 8;12(12):e1006513. doi: 10.1371/journal.pgen.1006513.

10. Qi ST, Ma JY, Wang ZB, Guo L, Hou Y, Sun QY*. N6-methyladenosine seqencing highlights the involvement of mRNA methylation in oocyte meiotic maturation and embryo development by regulating translation in Xenopus laevis. J Biol Chem. 2016 Oct 28;291(44):23020-23026.