Selected Publications:

　　1.     Zhou J#, Jin L, Wang F, Zhang Y, Liu B, Zhao T*. Chimeric antigen receptor T (CAR-T) cells expanded with IL-7/IL-15 mediate superior antitumor effects. Protein Cell. 2019, DOI: 10.1007/s13238-019-0643-y

　　2.     Gu H#, Shi X#, Liu C#, Wang W#, Shi N, Zhao Y, Gong J, Wang F, Zhang H, Li W*, Zhao T*. USP8 maintains embryonic stem cell stemness via deubiquitination of EPG5. Nature Communications, 2019, 10(1): 1465.

　　3.     Gong J#, Gu H#, Zhao L#, Wang L, Liu P, Wang F, Xu H, Zhao T*. Phosphorylation of ulk1 by ampk is essential for mouse embryonic stem cell self-renewal and pluripotency.  Cell Death & Disease, 2018, 9(2): 38.  

　　4.     Liu P#, Liu K#, Gu H, Wang W, Gong J, Zhu Y, Zhao Q, Cao J, Han C, Gao F, Chen Q, Li W, Jiao J, Hu B, Zhou Q, Zhao T*. High autophagic flux guards ESC identity through coordinating autophagy machinery gene program by FOXO1. Cell Death and Differentiation, 2017, 24(10): 1672-1680.

　　5.     Sun H#, Cao J#, Zhao L#, Zhu S, Chen S, Li Y, Zhao B, Zhao T*. PIM2 regulates stemness through phosphorylation of 4E-BP1. Science Bulletin, 2017, 62(10): 679-685. (Cover story).

　　6.     Liu K#, Zhao Q#, Liu P#, Cao J, Gong J, Wang C, Wang W, Li X, Sun H, Zhang C, Li Y, Jiang M, Zhu S, Sun Q, Jiao J, Hu B, Zhao X, Li W, Chen Q, Zhou Q*, Zhao T*. ATG3-dependent autophagy mediates mitochondrial homeostasis in pluripotency acquirement and maintenance. Autophagy, 2016, 12(11): 2000-2008.

　　7.     Zhu S, Cao J, Sun H, Liu K, Li Y, Zhao T*. p18 inhibits reprogramming through inactivation of Cdk4/6. Scientific Reports, 2016, 6: 31085.

　　8.     Zhang C, Cao J, Li X, Xu H, Wang W, Wang L, Zhao X, Li W, Jiao J, Hu B, Zhou Q*, Zhao T*. Treatment of multiple sclerosis by transplantation of neural stem cells derived from induced pluripotent stem cells. Science China Life Sciences, 2016, 59(9): 950-957.

　　9.     Zhao T#, Zhang Z#, Westenskow P#, Todorova D, Hu Z, Lin T, Rong Z, Kim J, He J, Wang M, Clegg D, Yang Y, Zhang K, Friedlander M, Xu Y*. Humanized mice reveal differential immunogenicity of cells derived from autologous induced pluripotent stem cells. Cell Stem Cell, 2015, 17(3): 353-359.

　　10.  Wang L#, Cao J#, Wang Y#, Lan T#, Liu L, Wang W, Jin N, Gong J, Zhang C, Teng F, Yan G, Li C, Li J, Wan H, Hu B, Li W, Zhao X, Qi Z*, Zhao T*, Zhou Q*. Immunogenicity and functional evaluation of iPSC-derived organs for transplantation. Cell Discovery, 2015, 1: 15015.

　　11.  Zhao T, Zhang Z, Rong Z, Xu Y*. Immunogenicity of induced pluripotent stem cells. Nature, 2011, 474(7350): 212-216. DOI: 10.1038/nature10135

　　o   Highlighted by Nature (Nature 474:165); Nature Medicine (Nature Medicine 17: 670)

　　o   Recommended by Faculty of 1000 (F1000.com/11136956)

　　o   Reported by Nature, Science, New York Time, New Scientist, ScienceDaily, UK Guardian, USA today et al.

　　Reviews

1. Wang L#, Ye X#, Zhao T*. The physiological roles of autophagy in the mammalian life cycle. Biological Reviews, 2019, 94: 503-516.
2. Cao J, Zhao T*. Single-cell sequencing delivers hematopoietic stem cell specification. Science Bulletin, 2016, 61(18): 1419-1421.
3. Liu K#, Song Y#, Yu H#, Zhao T*. Understanding the roadmaps to induced pluripotency. Cell Death and Disease, 2014, 5: e1232.
4. Cao J#, Li X#, Lu X, Zhang C, Yu H, Zhao T*. Cells derived from iPSC can be immunogenic – Yes or No? Protein Cell, 2014, 5(1): 1-3.
5.  Lu X, Zhao T*. Clinical therapy using iPSCs: hopes and challenges. Genomics Proteomics Bioinformatics, 2013, 11(5): 294-298.
6.  Zhao T, Xu Y*. p53 and stem cells: new developments and new concerns. Trends in Cell Biology, 2010, 20(3): 170-175.